The Pavilion for Women at Texas Children's Hospital
Aagaard Kjersti

Department

Department of Obstetrics & Gynecology, Maternal Fetal Medicine

Primary Location

Ben Taub General Hospital

Contact

1 Baylor Plaza
Jones 314
Houston, TX 77030
Phone: (713) 798-8360

Kjersti M. Aagaard-Tillery, MD, PhD

Associate Professor, Baylor College of Medicine
Department of Obstetrics & Gynecology, Division of Maternal-Fetal Medicine

Education

University of Utah School of Medicine
MFM, 2007

University of Minnesota at Minneapolis Medical School
OBG, 2004

University of Minnesota at Minneapolis Medical School
M.D., 2000

From Dr. Aagaard-Tillery

Dr. Aagaard is board certified in Obstetrics and Gynecology and Maternal-Fetal Medicine and a Fellow of the American College of Obstetrician Gynecologists. She specializes in the field of Maternal-Fetal Medicine, and has specialty clinical interests in preterm birth, stillbirth, maternal obesity and cardiac disorders, ultrasound diagnosis and testing for fetal anomalies and genetic disorders, and management of pregnancies complicated by infections. 

Dr. Aagaard’s research interests include both basic science investigations and translation into clinical research. She is internationally recognized for her work on maternal obesity and nutrition, genomics, the “microbiome” and prevention of preterm birth. Dr. Aagaard also actively conducts clinical research related to both cause and management of common perinatal fetal conditions (preterm birth, stillbirth and fetal growth abnormalities), alongside research in the implications of parallel maternal conditions and behavior (obesity, smoking, and nutrition).  

In addition to the Aagaard labs research on epigenetics, they are leading the way in unraveling secrets about our “microbiome.” Of the 100 trillion cells in our body, 90 trillion are microbial. This includes viruses, bacteria, parasites, and other microbes and are collectively referred to as our “microbiome.” Each of these has their own genomic codes, which regulate not only their metabolism but ours. For example, without bacteria we could not make Vitamin K, or convert most of our B vitamins to useable forms. We have recently demonstrated that the pregnancy microbiome is distinct, and in fact with 98% certainty we can actually tell if someone is pregnant simply by sequencing their vaginal microbiome. With respect to pregnancy, the Aagaard lab is funded to understand the microbiome and pregnancy complications leading to later in life diseases.  

Throughout her career and training she has raised three children on her own and remained an active member in the community. She is a recipient of the Houston Women’s Magazine “Maximum Mom” Award which is awarded “to a woman who has been an extraordinary mother to her children and mentor to others in providing strong moral character and serving as a role model.” 

Selected Publications

Aagaard-Tillery KM, Malone FD, Nyberg DA, Porter TF, Cuckle HS, Fuchs K, Sullivan L, Comstock CH, Saade GR, Eddleman K, Gross S, Dugoff L, Craigo SD, Timor-Tritsch IE, Carr SR, Wolfe HM, Bianchi DW, D'Alton ME. Role of second-trimester genetic sonography after Down syndrome screening. Obstetrics & Gynecology 2009 Dec;114(6):1189-96.

Harris RA, Ben-Shachar S, Facchinetti R, Saade G, Van den Veyver IB and Aagaard-Tillery KM. Genome-wide array-based copy number profiling in placentas from unexplained stillbirth. Prenatal Diagnosis 2011. Jul 5. doi: 10.1002/pd.2817.

Suter M, Bocock P, Showalter L, Hu M, Shope C, McKnight R, Grove K, Lane R, Aagaard-Tillery KM. Epigenomics: maternal high-fat diet exposure in utero disrupts peripheral circadian gene expression in nonhuman primates. FASEB Journal 2011 Feb;25(2):714-26.

The Human Microbiome Consortium. Structure, function and diversity of the human microbiome in an adult reference population.  (Roles: Data Analysis Working Group; Body Site Expert; Writing Group; Study Protocol Design; Clinical Investigator; Clinical Metadata Analysis) Nature 2012 Jun 13;486(7402):207-14. doi: 10.1038/nature11234. PMID: 22699609. 

Aagaard K, Riehle K, Ma J, Segata N, Mistretta TA, Coarfa C, Raza S, Rosenbaum S, Van den Veyver I, Milosavljevic A, Gevers D, Huttenhower C, Petrosino J, Versalovic J. A metagenomic based approach to characterization of the vaginal microbiome signature in pregnancy. PLoS One 2012;7(6):e36466. Epub 2012 Jun 13. PMID: 22719832.

Organizations

National Institutes of Health, NICHD
Pregnancy and Neonatology Study Section

Society for Maternal-Fetal Medicine
Member

American Academy of Pediatrics
Perinatal Advisory Board Member

Society for Gynecologic Investigation
Member, Committee Chair

National Institutes of Health, NICHD
Chairman, Vision 2010 “Developmental Origins of Disease”

Kjersti M. Aagaard-Tillery, MD, PhD

Aagaard Kjersti

Department

Department of Obstetrics & Gynecology, Maternal Fetal Medicine

Primary Location

Ben Taub General Hospital

Contact

1 Baylor Plaza
Jones 314
Houston, TX 77030
Phone: (713) 798-8360

Associate Professor, Baylor College of Medicine
Department of Obstetrics & Gynecology, Division of Maternal-Fetal Medicine

Education

University of Utah School of Medicine
MFM, 2007

University of Minnesota at Minneapolis Medical School
OBG, 2004

University of Minnesota at Minneapolis Medical School
M.D., 2000

From Dr. Aagaard-Tillery

Dr. Aagaard is board certified in Obstetrics and Gynecology and Maternal-Fetal Medicine and a Fellow of the American College of Obstetrician Gynecologists. She specializes in the field of Maternal-Fetal Medicine, and has specialty clinical interests in preterm birth, stillbirth, maternal obesity and cardiac disorders, ultrasound diagnosis and testing for fetal anomalies and genetic disorders, and management of pregnancies complicated by infections. 

Dr. Aagaard’s research interests include both basic science investigations and translation into clinical research. She is internationally recognized for her work on maternal obesity and nutrition, genomics, the “microbiome” and prevention of preterm birth. Dr. Aagaard also actively conducts clinical research related to both cause and management of common perinatal fetal conditions (preterm birth, stillbirth and fetal growth abnormalities), alongside research in the implications of parallel maternal conditions and behavior (obesity, smoking, and nutrition).  

In addition to the Aagaard labs research on epigenetics, they are leading the way in unraveling secrets about our “microbiome.” Of the 100 trillion cells in our body, 90 trillion are microbial. This includes viruses, bacteria, parasites, and other microbes and are collectively referred to as our “microbiome.” Each of these has their own genomic codes, which regulate not only their metabolism but ours. For example, without bacteria we could not make Vitamin K, or convert most of our B vitamins to useable forms. We have recently demonstrated that the pregnancy microbiome is distinct, and in fact with 98% certainty we can actually tell if someone is pregnant simply by sequencing their vaginal microbiome. With respect to pregnancy, the Aagaard lab is funded to understand the microbiome and pregnancy complications leading to later in life diseases.  

Throughout her career and training she has raised three children on her own and remained an active member in the community. She is a recipient of the Houston Women’s Magazine “Maximum Mom” Award which is awarded “to a woman who has been an extraordinary mother to her children and mentor to others in providing strong moral character and serving as a role model.” 

Selected Publications

Aagaard-Tillery KM, Malone FD, Nyberg DA, Porter TF, Cuckle HS, Fuchs K, Sullivan L, Comstock CH, Saade GR, Eddleman K, Gross S, Dugoff L, Craigo SD, Timor-Tritsch IE, Carr SR, Wolfe HM, Bianchi DW, D'Alton ME. Role of second-trimester genetic sonography after Down syndrome screening. Obstetrics & Gynecology 2009 Dec;114(6):1189-96.

Harris RA, Ben-Shachar S, Facchinetti R, Saade G, Van den Veyver IB and Aagaard-Tillery KM. Genome-wide array-based copy number profiling in placentas from unexplained stillbirth. Prenatal Diagnosis 2011. Jul 5. doi: 10.1002/pd.2817.

Suter M, Bocock P, Showalter L, Hu M, Shope C, McKnight R, Grove K, Lane R, Aagaard-Tillery KM. Epigenomics: maternal high-fat diet exposure in utero disrupts peripheral circadian gene expression in nonhuman primates. FASEB Journal 2011 Feb;25(2):714-26.

The Human Microbiome Consortium. Structure, function and diversity of the human microbiome in an adult reference population.  (Roles: Data Analysis Working Group; Body Site Expert; Writing Group; Study Protocol Design; Clinical Investigator; Clinical Metadata Analysis) Nature 2012 Jun 13;486(7402):207-14. doi: 10.1038/nature11234. PMID: 22699609. 

Aagaard K, Riehle K, Ma J, Segata N, Mistretta TA, Coarfa C, Raza S, Rosenbaum S, Van den Veyver I, Milosavljevic A, Gevers D, Huttenhower C, Petrosino J, Versalovic J. A metagenomic based approach to characterization of the vaginal microbiome signature in pregnancy. PLoS One 2012;7(6):e36466. Epub 2012 Jun 13. PMID: 22719832.

Organizations

National Institutes of Health, NICHD
Pregnancy and Neonatology Study Section

Society for Maternal-Fetal Medicine
Member

American Academy of Pediatrics
Perinatal Advisory Board Member

Society for Gynecologic Investigation
Member, Committee Chair

National Institutes of Health, NICHD
Chairman, Vision 2010 “Developmental Origins of Disease”