Christopher A. Caldarone, MD

Education

School	Education	Degree	Year
Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, MA	Residency	Cardiothoracic Surgery	1998
The Hospital for Sick Children, Toronto, Ontario, Canada	Fellowship	Congenital Heart Surgery	1997
Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, MA	Residency	General Surgery	1995
Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, MA	Fellowship	Research	1993
Columbia University College of Physicians and Surgeons, New York City, New York	Medical School	Doctor of Medicine	1988
Johns Hopkins University, Baltimore, MD	Bachelors	Bachelor of Arts	1984

Personal Statement

Congenital heart surgery requires integrated teamwork from cardiologists, cardiac intensivists, cardiac anesthetists, specialized nurses, and cardiac surgeons. At Texas Children's Hospital, our Heart Center will bring these groups together to provide the best care achievable for patients with congenital heart disease. With this collaborative framework, we will insure that every patient has the full benefit of the expertise of the entire Heart Center for all aspects of care.

Dr. Caldarone moved to Texas Children’s Hospital from the Hospital for Sick Children in Toronto where he served as the University Chair of Cardiac Surgery (2009-2016) and as the Surgeon-in-Chief and Chief of Perioperative Services (2015-2018). Dr. Caldarone joined the team at Texas Children’s Hospital as the Chief of Congenital Heart Surgery in September of 2018. Throughout his career, Dr Caldarone has maintained international leadership roles in the Congenital Heart Surgeons Society, the Society of Thoracic Surgeons, and the American Association for Thoracic Surgery.

Clinical Interests:

Dr. Caldarone specializes in the management of children and adults with congenital heart disease. His main clinical interests include the treatment of left ventricular outflow tract obstruction, coronary anomalies, and pulmonary vein stenosis.

Research Interests:

Dr. Caldarone’s specific interest include the role of apoptosis related mitochondrial dysfunction and remote ischemic preconditioning as mediators of reperfusion injury. Most recently, Dr. Caldarone has focused on pulmonary vein stenosis and tissue engineering of pulmonary valves.

Organization

Organization Name	Role
American Association for Thoracic Surgery	Member
American Heart Association	Member; Cardiovascular Surgery and Anesthesia (CVSA) Nominating Committee
Congenital Heart Surgeons' Society	Member
Society of Thoracic Surgeons	Member

Selected Publications

Tremblay C, Yoo SJ, Mertens L, Seed M, Jacques F, Slorach C, Vanderlaan R, Greenway S, Caldarone C, Coles J, Grosse-Wortmann L. (2018). Sutureless Versus Conventional Pulmonary Vein Repair: A Magnetic Resonance Pilot Study. The Annals of Thoracic Surgery 105(4): 1248-1254.

Vanderlaan RD, Caldarone CA. (2018). [Editorial Commentary] Sutureless repair and postoperative residual stenosis: "Never leave with a lesion". The Journal of Thoracic and Cardiovascular Surgery 156(1): 287-288.

Vanderlaan RD, Caldarone CA. (2018). Surgical Approaches to Total Anomalous Pulmonary Venous Connection. Seminars in Thoracic and Cardiovascular Surgery: Pediatric Cardiac Surgery Annual 21: 83-91.

Vanderlaan RD, Caldarone CA. (2018). Decompressing extrinsic pulmonary vein obstruction. The Journal of Thoracic and Cardiovascular Surgery 155(2): e71-e72.

Rodriguez ML, Caldarone CA, Toeg H, Maharajh G. (2017). Retroesophageal Infracardiac Total Anomalous Pulmonary Venous Drainage. World Journal for Pediatric & Congenital Heart Surgery In Press.

Mahgoub L, Kaddoura T, Kameny AR, Lopez Ortego P, Vanderlaan RD, Kakadekar A, Dicke F, Rebeyka I, Caldarone CA, Redington A, Del Cerro MJ, Fineman J, Adatia I. (2017). Pulmonary vein stenosis of ex-premature infants with pulmonary hypertension and bronchopulmonary dysplasia, epidemiology, and survival from a multicenter cohort. Pediatric Pulmonology 52(8): 1063-1070.

Zhu J, Meza J, Kato A, Saedi A, Chetan D, Parker R, Caldarone CA, McCrindle BW, Van Arsdell GS, Honjo O. (2016). Pulmonary flow study predicts survival in pulmonary atresia with ventricular septal defect and major aortopulmonary collateral arteries. The Journal of Thoracic and Cardiovascular Surgery 152(6): 1494-1503.e1.

Lo Rito M, Gazzaz T, Wilder TJ, Vanderlaan RD, Van Arsdell GS, Honjo O, Yoo SJ, Caldarone CA. (2016). Pulmonary vein stenosis: Severity and location predict survival after surgical repair. The Journal of Thoracic and Cardiovascular Surgery 151(3): 657-666.e2.

Vanderlaan RD, Caldarone CA. (2016). The Ongoing Evolution of Sutureless Repairs for Pulmonary Vein Anomalies. Seminars in Thoracic and Cardiovascular Surgery: Pediatric Cardiac Surgery Annual 28(2): 485-486.

Lo Rito M, Gazzaz T, Wilder T, Saedi A, Chetan D, Van Arsdell GS, Caldarone CA, Yoo SJ, Honjo O. (2015). Repair Type Influences Mode of Pulmonary Vein Stenosis in Total Anomalous Pulmonary Venous Drainage. The Annals of Thoracic Surgery 100(2): 654-62.

Kotani Y, Zhu J, Grosse-Wortmann L, Honjo O, Coles JG, Van Arsdell GS, Caldarone CA. (2015). Anatomical risk factors, surgical treatment, and clinical outcomes of left-sided pulmonary vein obstruction in single-ventricle patients. The Journal of Thoracic and Cardiovascular Surgery 149(5): 1332-8.

Kato H, Fu YY, Zhu J, Wang L, Aafaqi S, Rahkonen O, Slorach C, Traister A, Leung CH, Chiasson D, Mertens L, Benson L, Weisel RD, Hinz B, Maynes JT, Coles JG, Caldarone CA. (2014). Pulmonary vein stenosis and the pathophysiology of "upstream" pulmonary veins. The Journal of Thoracic and Cardiovascular Surgery 148(1): 245-53.

Zhu J, Kotani Y, Chetan D, Zhao L, Coles JG, Caldarone CA, Van Arsdell GS, Honjo O. (2014). Is restrictive atrial septal defect a risk in partial anomalous pulmonary venous drainage repair?. The Annals of Thoracic Surgery 97(5): 1664-70.

Caldarone LA, Caldarone CA, Vricella LA. (2014). Retroesophageal total anomalous pulmonary venous connection in a neonate. The Journal of Thoracic and Cardiovascular Surgery 148(2): e143-5.

Zhu J, Ide H, Fu YY, Teichert AM, Kato H, Weisel RD, Maynes JT, Coles JG, Caldarone CA. (2014). Losartan ameliorates "upstream" pulmonary vein vasculopathy in a piglet model of pulmonary vein stenosis. The Journal of Thoracic and Cardiovascular Surgery 148(6): 2550-7.

Hickey EJ, Caldarone CA. (2011). Surgical Management of Post-repair Pulmonary Vein Stenosis. Seminars in Thoracic and Cardiovascular Surgery: Pediatric Cardiac Surgery Annual 14(1): 101-8.

Yoo SJ, Caldarone CA. (2016). Pulmonary vein stenosis: Severity and location predict survival after surgical repair. The Journal of Thoracic and Cardiovascular Surgery 151(3): 657-666.e2.

View PubMed Publications