Xanthi I. Couroucli, MD


School Education Degree Year
Baylor College of Medicine fellowship Neonatal-Perinatal Medicine 1999
Children's National Medical Center university Pediatric Cardiology 1996
Medical Center residency Pediatrics 1995
University of Oxford residency Rotating Residency 1990
Hammersmith Hospital-England residency Rotating Residency 1990
University of Oxford internship Rotating Internship 1990
Oxford Radcliffe Hospital NHS Trust internship Rotating Internship 1990
University of Athens medical school Doctor of Medicine 1987

Personal Statement

Professional Interests:


Prevention of Hyperoxic Lung Injury

Prevention of Retinopathy of Prematurity

Vitamin A research

Research on Cytochrome P450

Prevention of effects of maternal smoking in the newborn

Honors & Awards:

Young Investigator Award American Academy of Pediatrics (10/2000)

Young Scientist Travel Award American Society for Pharmacology and Experimental Therapeutics (03/2001)

KO8 mentored Award NHLBI (09/2001 - 08/2008) Mentored Award for 850,000 USD for my research with title: "Cytochrome P450 regulation by hyperoxia and nitric oxide" RO1 grant AWARD from NIH :Role of hepatic and pulmonary P4501A enzymes in neonatal hyperoxic tissue injury NHLBI (09/2009 - 08/2015)

RO1 grant with title: "Role of hepatic and pulmonary P4501A enzymes in neonatal hyperoxic tissue injury" Total amount of grant: 1,900,000 USD


Organization Name Role
American Academy of Pediatrics FAAP
General Medical Council, UK Member

Selected Publications

Jiang W, Wang L, Kondraganti SR, Fazili IS, Couroucli XI, Felix EA, Moorthy B. "Disruption of the gene for CYP1A2, which is expressed primarily in liver, leads to differential regulation of hepatic and pulmonary mouse CYP1A1 expression and augmented human CYP1A1 transcriptional activation in response to 3-methylcholanthrene in vivo.." J. Pharmacol. Exp. Ther.. 2010 November;335(2):369-79. Pubmed PMID: 20732958.

Zhou GD, Zhu H, Phillips TD, Wang J, Wang SZ, Wang F, Amendt BA, Couroucli XI, Donnelly KC, Moorthy B. "Effects of Dietary Fish Oil on the Depletion of Carcinogenic PAH-DNA Adduct Levels in the Liver of B6C3F1 Mouse.." PLoS ONE. 2011;6(10):e26589. Pubmed PMID: 22066002.

Couroucli XI, Liang YH, Jiang W, Wang L, Barrios R, Yang P, Moorthy B. "Prenatal administration of the cytochrome P4501A inducer, ?-naphthoflavone (BNF), attenuates hyperoxic lung injury in newborn mice: Implications for bronchopulmonary dysplasia (BPD) in premature infants.." Toxicol. Appl. Pharmacol.. 2011 October 15;256(2):83-94. Pubmed PMID: 21745492.

Bhakta KY, Jiang W, Couroucli XI, Fazili IS, Muthiah K, Moorthy B. "Regulation of cytochrome P4501A1 expression by hyperoxia in human lung cell lines: Implications for hyperoxic lung injury.." Toxicol. Appl. Pharmacol.. 2008 December 1;233(2):169-78. Pubmed PMID: 18824009.

Couroucli XI, Welty SE, Ramsay PL, Wearden ME, Fuentes-Garcia FJ, Ni J, Jacobs TN, Towbin JA, Bowles NE. "Detection of microorganisms in the tracheal aspirates of preterm infants by polymerase chain reaction: association of adenovirus infection with bronchopulmonary dysplasia.." Pediatr. Res.. 2000 February;47(2):225-32. Pubmed PMID: 10674351.